Melkko, Samu: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

1

Isolation of High-Affinity Trypsin Inhibitors from a DNA-Encoded Chemical Library

Samu Melkko, Yixin Zhang, Christoph E. Dumelin, Jörg Scheuermann, Dario Neri

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 359 KB

english, 2007

2

Preparation of a Compound Dilution Series

Dreier, Oliver, Brasse, Hannah, Ingles, Sara, Schweigler, Patrick, Melkko, Samu

Journal:

Genetic Engineering & Biotechnology News

Year:

2013

Language:

english

File:

PDF, 240 KB

english, 2013

3

MAA868—a novel FXI antibody with a unique binding mode—shows durable effects on markers of anticoagulation in humans

Koch, Alexander W., Schiering, Nikolaus, Melkko, Samu, Ewert, Stefan, Salter, Janeen, Zhang, Yiming, McCormack, Peter, Yu, Jianying, Huang, Xueming, Chiu, Yu-Hsin, Chen, Zhiping, Schleeger, Simone, Ho

Journal:

Year:

2019

File:

PDF, 862 KB

2019

4

DNA-Encoded Chemical Libraries

Christoph E. Dumelin, Jörg Scheuermann, Samu Melkko, Dario Neri

Journal:

Molecular Informatics

Year:

2006

Language:

english

File:

PDF, 405 KB

english, 2006

5

Stabilizing Inactive Conformations of MALT1 as an Effective Approach to Inhibit Its Protease Activity

Hughes, Nicola, Erbel, Paul, Bornancin, FrÃ©dÃ©ric, Wiesmann, Christian, Schiering, Nikolaus, Villard, FrÃ©dÃ©ric, Decock, Arnaud, Rubi, Bertran, Melkko, Samu, Spanka, Carsten, Buschmann, Nicole, Piss

Journal:

Advanced Therapeutics

Year:

2020

File:

PDF, 3.55 MB

2020

6

Encoded Self-Assembling Chemical Libraries

Melkko, Samu, Sobek, Jens, Guarda, Greta, Scheuermann, Jörg, Dumelin, Christoph E., Neri, Dario

Journal:

CHIMIA International Journal for Chemistry

Year:

2005

Language:

english

File:

PDF, 2.97 MB

english, 2005

7

Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood

Quancard, Jean, Simic, Oliver, Pissot Soldermann, Carole, Aichholz, Reiner, Blatter, Markus, Renatus, Martin, Erbel, Paulus, Melkko, Samu, Endres, Ralf, Sorge, Mickael, Kieffer, Laurence, Wagner, Trix

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 2.37 MB

2020

8

Discovery and Structure-Based Optimization of Adenain Inhibitors

Mac Sweeney, Aengus, Grosche, Philipp, Ellis, David, Combrink, Keith, Erbel, Paul, Hughes, Nicola, Sirockin, Finton, Melkko, Samu, Bernardi, Anna, Ramage, Paul, Jarousse, Nadine, Altmann, Eva

Journal:

ACS Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 2.49 MB

english, 2014

9

Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing

Pissot Soldermann, Carole, Simic, Oliver, Renatus, Martin, Erbel, Paulus, Melkko, Samu, Wartmann, Markus, Bigaud, Marc, Weiss, Andreas, McSheehy, Paul, Endres, Ralf, Santos, Paulo, Blank, Jutta, Schuf

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 3.50 MB

2020

10

Isolation of a Small-Molecule Inhibitor of the Antiapoptotic Protein Bcl-xL from a DNA-Encoded Chemical Library

Samu Melkko, Luca Mannocci, Christoph E. Dumelin, Alessandra Villa, Roberto Sommavilla, Yixin Zhang, Markus G. Grütter, Nadine Keller, Lutz Jermutus, Ronald H. Jackson, Jörg Scheuermann, Dario Neri

Journal:

Year:

2010

Language:

english

File:

PDF, 916 KB

english, 2010

11

Two General Methods for the Isolation of Enzyme Activities by Colony Filter Screening

Christian Heinis, Samu Melkko, Salvatore Demartis, Dario Neri

Journal:

Chemistry & Biology

Year:

2002

Language:

english

File:

PDF, 285 KB

english, 2002

12

On the Magnitude of the Chelate Effect for the Recognition of Proteins by Pharmacophores Scaffolded by Self-Assembling Oligonucleotides

Samu Melkko, Christoph E. Dumelin, Jörg Scheuermann, Dario Neri

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 567 KB

english, 2006

13

DNA-Encoded Chemical Libraries for the Discovery of MMP-3 Inhibitors

Scheuermann, Jörg, Dumelin, Christoph E., Melkko, Samu, Zhang, Yixin, Mannocci, Luca, Jaggi, Madalina, Sobek, Jens, Neri, Dario

Journal:

Bioconjugate Chemistry

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

14

Structural Determinants of MALT1 Protease Activity

Christian Wiesmann, Lukas Leder, Jutta Blank, Anna Bernardi, Samu Melkko, Arnaud Decock, Allan D'Arcy, Frederic Villard, Paulus Erbel, Nicola Hughes, Felix Freuler, Rainer Nikolay, Juliano Alves, Fred

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 2.14 MB

english, 2012

15

Isolation of High-Affinity Trypsin Inhibitors from a DNA-Encoded Chemical Library

Samu Melkko, Yixin Zhang, Christoph E. Dumelin, Jörg Scheuermann, Dario Neri

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 359 KB

english, 2007

16

Fragment-Based Protein-Protein Interaction Antagonists of a Viral Dimeric Protease

Gable, Jonathan E., Lee, Gregory M., Acker, Timothy M., Hulce, Kaitlin R., Gonzalez, Eric R., Schweigler, Patrick, Melkko, Samu, Farady, Christopher J., Craik, Charles S.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

17

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling

Klein, Theo, Fung, Shan-Yu, Renner, Florian, Blank, Michael A., Dufour, Antoine, Kang, Sohyeong, Bolger-Munro, Madison, Scurll, Joshua M., Priatel, John J., Schweigler, Patrick, Melkko, Samu, Gold, Mi

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 5.24 MB

english, 2015

18

Encoded self-assembling chemical libraries

Melkko, Samu, Scheuermann, Jörg, Dumelin, Christoph E, Neri, Dario

Journal:

Nature Biotechnology

Year:

2004

Language:

english

File:

PDF, 549 KB

english, 2004

19

Selection of Streptavidin Binders from a DNA-Encoded Chemical Library

Dumelin, Christoph E., Scheuermann, Jörg, Melkko, Samu, Neri, Dario

Journal:

Bioconjugate Chemistry

Year:

2006

Language:

english

File:

PDF, 235 KB

english, 2006

20

Lead discovery by DNA-encoded chemical libraries

Samu Melkko, Christoph E. Dumelin, Jörg Scheuermann, Dario Neri

Journal:

Drug Discovery Today

Year:

2007

Language:

english

File:

PDF, 850 KB

english, 2007

21

DNA-encoded chemical libraries

Jörg Scheuermann, Christoph E. Dumelin, Samu Melkko, Dario Neri

Journal:

Journal of Biotechnology

Year:

2006

Language:

english

File:

PDF, 917 KB

english, 2006

22

Structure-based design and optimization of potent inhibitors of the adenoviral protease

Grosche, Philipp, Sirockin, Finton, Mac Sweeney, Aengus, Ramage, Paul, Erbel, Paul, Melkko, Samu, Bernardi, Anna, Hughes, Nicola, Ellis, David, Combrink, Keith D., Jarousse, Nadine, Altmann, Eva

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.41 MB

english, 2015

23

An antibody-calmodulin fusion protein reveals a functional dependence between macromolecular isoelectric point and tumor targeting performance

Samu Melkko, Cornelia Halin, Laura Borsi, Luciano Zardi, Dario Neri

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2002

Language:

english

File:

PDF, 216 KB

english, 2002

24

Isolation of Potent and Specific Trypsin Inhibitors from a DNA-Encoded Chemical Library

Mannocci, Luca, Melkko, Samu, Buller, Fabian, Molnàr, Ilona, Gapian Bianké, Jean-Paul, Dumelin, Christoph E., Scheuermann, Jörg, Neri, Dario

Journal:

Bioconjugate Chemistry

Year:

2010

Language:

english

File:

PDF, 2.74 MB

english, 2010

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски